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J FAS Int 2003;1:e2 - The History of Alcoholic Fetopathies

Paul Lemoine, MD, Nantes, France

Around 1960, I was struck by the existence of a yet unknown syndrome in children which included severe intrauterine growth retardation. The syndrome resulted in significant and lasting hypotrophy, microcephaly, psychomotor retardation and behavioral problems, as well a very specific facial dysmorphology and frequent malformations. One day, I was comparing two of these children looking for an answer, and while talking to the staff as I always did, one of them indicated to me that their mothers were heavily alcohol dependent. And the spark hit!

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