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Eutectic Mixture of Local Anesthetics (EMLA): A Breakthrough in Skin Anesthesia

edited by Gideon Koren MD, Marcel Dekker, Inc. 1995

Expert review by international clinicians/scientists of EMLA's efficacy and safety in a variety of indications. The technological breakthrough that led to the introduction of the EMLAs has marked a new chapter in medical thinking as it relates to iatrogenic-procedural pain.

To order, click here.


1. Pharmacology of Local Anesthetics
Doreen Matsui
2. Clinical Pharmacology and Toxicology of EMLA
Pascale Burtin and Shinya Ito
3. Use of EMLA in Infants and Children Undergoing Venipuncture
Gideon Koren, Isabelle Robieux and Daniel S. Halperin
4. Topical Skin Anesthesia for Subcutaneous Drug Reservoir and Lumbar Punctures in Children
Gideon Koren, Daniel S. Halperin, Marinette Wyss and Joseph Kapelushnik
5. Use of EMLA Cream and EMLA Patch in Outpatient Clinics
Gideon Koren, Chrisoula Eliopoulos, Shyam Radhakrishnan, Ram Kumar, Paul Hwang and Isabelle Robieux
6. EMLA for Neonatal Circumcision
Madlen Gazarian
7. Use of EMLA Cream as a Local Anesthetic for Laceration Repair
Michael J. Rieder
8. Effect of Lidocaine-Prilocaine Cream (EMLA) on Injection and Vaccination Pain
Anna Taddio and Gideon Koren
9. EMLA Cream for Pain Relief During Arterial Cannulation
Laura A. Magee
10. Use of EMLA Cream in Dermatosurgical Interventions of Skin and Genital Mucosa
Arnold P. Oranje and Flora B. de Waard-van der Spek
11. Use of EMLA Sterile Cream in the Management of Leg Ulcers
Donald Rosenthal
12. Use of EMLA Cream in Hemodialysis Patients
Izhar Ul Qamar
13. The Emerging Role of EMLA Cream in Lithotripsy
Kathleen Shilalukey
14. Use of EMLA Cream in Otolaryngology
Doreen Matsui and Matitiahu Berkovitch
15. The Role of EMLA Cream in Split Skin Harvesting
Lennart Ohlsen
16. A Study Investigating the Use of EMLA for Chronic Subcutaneous Drug Administration
Matitiahu Berkovitch, Susan Davis Lethbridge, Judy Donsky, Richard Hackman, Graham Sher, Gideon Koren, Nancy Olivieri, Doreen Matsui
17. The Impact of EMLA on the Ethics of Pediatric Research
Gideon Koren
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