- Morning Sickness
- Drugs in Pregnancy
- Alcohol, Nicotine, Substance Use
- Folic Acid
- Breastfeeding & Drugs
- Cancer in Pregnancy
- HIV and HIV Treatment
- Conditions in Pregnancy
- Infectious Diseases in Pregnancy
- Occupational & Environmental Exposures
- Pharmacokinetics/ Drug Metabolism
- The ReproPsych Group
- CAS Newsletter
1-877-327-4636 Alcohol and Substance
1-800-436-8477 Morning Sickness
1-888-246-5840 HIV and HIV Treatment
1-877-439-2744 Motherisk Helpline
416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
2013 FACE meeting
Fetal Alcohol Canadian Expertise (FACE) Satellite Meeting .
- Read more in our News Archive
Current Studies at Motherisk
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Environmental Exposures and Children's Health
Alcohol Use during Pregnancy
Control of Hypertension in Pregnancy Study
Folic Acid Before and During Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
Motherisk News: Motherisk researchers find prenatal multivitamins effective in preventing wide range of serious birth defects
Researchers at Motherisk have found that prenatal vitamins fortified with folic acid can reduce the risk of a wide range of serious birth defects, including cardiovascular and limb defects, cleft palate, oral cleft, congenital hydrocephalus and urinary tract anomalies. This research is reported in the August 2006 issue of the Journal of Obstetrics and Gynecology of Canada.
The study examined the findings of 41 other research publications exploring the effects of multivitamin supplementation before conception and during the first trimester. This is the first systematic review of the evidence linking multivitamins to reduced risk of birth defects other than neural tube defects. The study did not find links between the multivitamins and the prevention of Down syndrome, pyloric stenosis, undescended testis or hypospadias.
"Clearly, this information is very important for any woman looking to give her baby the healthiest start possible," says Dr. Gideon Koren, the study's principal investigator and director of the Motherisk Program. "And with as many as one out of every 33 children in Canada being born with a serious congenital birth defect, this information has the power to make a big difference in the lives of many people."
As the study examined multivitamins containing folic acid in general, additional research is needed to determine which specific vitamins provide which protective effects, and to determine how much of the protective effects is attributable specifically to folic acid.
Other authors on the paper were Ingrid Goh and Enkelejde Bollano of SickKids and Thomas Einarson of the University of Toronto.
This research was supported by the Canadian Institutes of Health Research and the Research Leadership for Better Pharmacotherapy During Pregnancy and Lactation.