1-877-439-2744 Motherisk Helpline
1-800-436-8477 Morning Sickness
1-877-327-4636 Alcohol and Substance
1-866-937-7678 Exercise in Pregnancy
1-888-246-5840 HIV and HIV Treatment
416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
Current Studies at Motherisk
The Safety of Diclectin in Breastfeeding
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Alcohol Use during Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
Conditions in Pregnancy
Play video of the Keynote Address of the 2008 Motherisk Update
[ 152MB - Windows Media File ]
Mood Disorders in Women: Focus on Reproductive TransitionsVivien K. Burt, MD, PhD
Abstract: Women are at increased risk for mood disorders from the time of puberty onward. While there are many factors that explain this increased risk, it is becoming increasingly clear that for some women, reproductive transitions represent times of particular risk for new onset and recurrent depression. For example, puberty marks the beginning of the increased risk for depression in women. Most women report physical or emotional symptoms premenstrually with some severe enough to be diagnosed as premenstrual dysphoric disorder. Increasing data suggests that antenatal depression is not rare, particularly in women with past histories of depression or other mood disorders. Women who discontinue treatment with medications that keep them emotionally well upon learning that they are pregnant are particularly vulnerable to relapse or recurrence during pregnancy and the postpartum. Hormonal changes during the postpartum increase the incidence of depression and other mood disorders, and this is particularly troubling as the postpartum is a time when women are responsible not just for their own health and well-being but also the well-being of their babies and other children. Similarly, women transitioning through the years leading to menopause are at increased risk for depression, both recurrent and new-onset. Other times of hormonal challenge which are now believed to be associated with mood instability in women are post-miscarriage and during treatment for infertility. The use of reproductive transitional events as markers, the latest data on prophylaxis, and treatment of reproductive related mood disorders are discussed.
Certain chronic conditions and their treatment may increase reproductive risks. Click on any of the links below to find Motherisk's published studies on various conditions in pregnancy.
Approximately 20% of women experience NVP for a longer period of time. Some women may suffer from NVP until the end of the pregnancy.
Pregnancy, whether planned or a pleasant surprise, brings with it important concerns about prescription and over the counter drugs.
There are several agents for which safety during breast-feeding is not well-defined and may be a risk to the infant.
Certain chronic conditions and their treatment may increase reproductive risks.
There are thousands of chemicals in use in today's workplaces - and more women at work than ever before.
Natural doesn't always mean safe. But that doesn't stop millions of people, including pregnant women, from consuming naturopathic products.