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Exposures in Pregnancy: In-Utero Exposure to Drugs - Monitoring and biological markers

Motherisk Research

  • Hum Exp Toxicol. 1999 Apr;18(4):279-8
    Klein J, Koren G: Hair analysis--a biological marker for passive smoking in pregnancy and childhood.
  • Forens Sci Intl 70: 77-82, 1995.
    Koren G: Measurement of drugs in neonatal hair: A window to fetal exposure.
  • [Review][15 refs] [Hebrew] Harefuah. 129(9):336-8, 1995 Nov 1. No Abstract available.
    Ben David S. Measurement of drugs in neonatal hair--a window to fetal exposure]
  • N Engl J Med 328: 66-67, 1993.
    Klein J, Chitayat D, Koren G: Hair as a biological marker for intrauterine exposure to cigarette smoking
  • http://www.ncbi.nlm.nih.gov/pubmed/1306811
    Koren G, Klein J, Forman R, Graham K, My-Khan P: Biological Markers of intrauterine exposure to cocaine and cigarette smoking. Dev Pharmacol Ther 18: 228-236, 1992.
  • JAMA 271(8):621-3, 1994.
    Eliopoulos C, Klein J, Phan MK, Knie B, Greenwald M, Chitayat D, Koren G: Hair concentrations of nicotine and cotinine in women and newborn infants.
  • J Clin Pharmacol 32: 671-675, 1992.
    Koren G, Klein J, Forman R, Graham K: Hair Analysis of cocaine: Differentiation between systemic exposure and external contamination.
  • Koren G, Klein J, Graham K, Forman R: Hair test to varify gestational cocaine exposure. In: Recent Developments in TDM and Clin Toxicology Marcel Dekker, NY 569-574, 1992.
    In Book:
  • http://www.researchgate.net/
    Graham K, Klein J, Forman R, Flynnk, Sakuma T, Davidson W, Koren G: Potential misclassification of a case of SIDS: Maternal and neonatal hair analysis for cocaine and heroin. Maternal Fetal Med 2: 91-93, 1993.
  • Johnson D, Schwartz H, Forman R, Klein J, Jacobson, S, Greenwald M, Koren G: Assessment of in utero exposure to cocaine; Radioimmunoassay testing for benzoylecgonine in meconium, neonatal hair and maternal hair. Can J Clin Pharmacol 1: 83-86, 1994.
  • JAMA 262: 3328-3330, 1989.
    Graham K, Koren g, Klein J, Schneiderman J: Determination of gestational cocaine exposure by hair analysis.
  • Eliopoulos C, Klein J, Koren G: Neonatal markers for intrauterine exposure to cocaine and nicotine. Can J Obstet Gynecol 6: 615-620, 1994.
  • Life Sci 50: 1333-1341, 1992.
    Forman R, Graham K, Klein J, Greenwald M, Koren G: Accumulation of cocaine in fetal hair; The dose response curve.
  • Koren G: TDM in Pregnacy. In: Recent developments in TDM and Clinical Toxicology, Marcel Dekker, NY, pp 53-62, 1992.
    In Book:
  • Drug Intell Clin Pharm 22: 813-824, 1988.
    Einarson TR, Leeder JS, Koren G: A Method for meta analysis of epidemiological studies.
  • Koren G, Ben David S: Drug and Chemical monitoring using neonatal hair. Is Med Assoc J 129:336-338, 1995.
  • J Toxicol Clin Toxicol 2001; 39: 361-6.
    Ursitti F, Klein J, Sellers E, Koren G: Use of hair analysis for confirmation of self-reported cocaine use in users with negative urine tests.
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The information on this website is not intended as a substitute for the advice and care of your doctor or other health-care provider. Always consult your doctor if you have any questions about exposures during pregnancy and before you take any medications.

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The Hospital for Sick Children (SickKids) is a health-care, teaching and research centre dedicated exclusively to children; affiliated with the University of Toronto. For general inquires please call: 416-813-1500.

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