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The Cancer in Pregnancy Forum

Archived Questions and Answers
This Forum has been the centre of an exceptional exchange of knowledge diagnosis, treatment, symptoms and other effects of cancer during pregnancy and lactation. All are welcome to review the Questions and Answers posted here, provided that they acknowledge and accept the important proviso and disclaimer below.
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Forum > Specific Cancer: Specific Cancer
AML in pregnancy

Date: 2000-07-19

An 18 year old married female pregnant at 29 wks primigravida, presented with AML M2.WBC 150x10(9)/L Platelet count 40x10(9)/L. So far she is in good condition. She has no organomegaly,LFT,U/Es,coagulation profile are unremarkable. Feotus status is satisfactory. Options for management?

The treatment of leukemia should not be delayed much longer. Since she is in the 29th week of pregnancy, the fetus is relatively secure. On the other hand the treatment should not be too agressive in order to avoid severe leukopenia and thrombocytopenia that could harm the mother and baby. Therefore the treatment should probably be started gently with reduced doses of ARA-C or hydroxyurea. Labour should be induced when the fetus is mature and the mother's blood counts enable it. After delivery the mother should be treated agressively for leukemia according to usual protocols.

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