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The Cancer in Pregnancy Forum

Archived Questions and Answers
This Forum has been the centre of an exceptional exchange of knowledge diagnosis, treatment, symptoms and other effects of cancer during pregnancy and lactation. All are welcome to review the Questions and Answers posted here, provided that they acknowledge and accept the important proviso and disclaimer below.
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Forum > Chemotherapy: Paternal
Paternal exposure to hydroxyurea

CCoPE
Date: 2004-05-02

Question:
I am a haematologist from south Brazil (Porto Alegre)and have a patient (male)that had an acute miocardial infarction 8 years ago. In this moment your platelet count was 1,2 million/mm3. I start hydroxiurea and had a good response. Now, his wife intend to get pregnant and he ask me about the hydroxiurea X anagrelide risks. I dont find specific articles about this, only recomendation to suspend hydroxiurea 3 months before conception. Could you help me?

Answer:
It seems that a patient with ET who has undergone myocardial infarction cannot discontinue the hydroxyurea. To our knowledge, there are no reports on damage to fetuses that were conceived when the fathers were taking hydroxyurea.

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