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I am a haematologist from south Brazil (Porto Alegre)and have a patient (male)that had an acute miocardial infarction 8 years ago. In this moment your platelet count was 1,2 million/mm3. I start hydroxiurea and had a good response. Now, his wife intend to get pregnant and he ask me about the hydroxiurea X anagrelide risks. I dont find specific articles about this, only recomendation to suspend hydroxiurea 3 months before conception. Could you help me?
It seems that a patient with ET who has undergone myocardial infarction cannot discontinue the hydroxyurea. To our knowledge, there are no reports on damage to fetuses that were conceived when the fathers were taking hydroxyurea.