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Eutectic Mixture of Local Anesthetics (EMLA): A Breakthrough in Skin Anesthesia

edited by Gideon Koren MD, Marcel Dekker, Inc. 1995

Expert review by international clinicians/scientists of EMLA's efficacy and safety in a variety of indications. The technological breakthrough that led to the introduction of the EMLAs has marked a new chapter in medical thinking as it relates to iatrogenic-procedural pain.

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Contents: Preface Contributors		iii ix
1.	Pharmacology of Local Anesthetics Doreen Matsui	1
2.	Clinical Pharmacology and Toxicology of EMLA Pascale Burtin and Shinya Ito	17
3.	Use of EMLA in Infants and Children Undergoing Venipuncture Gideon Koren, Isabelle Robieux and Daniel S. Halperin	37
4.	Topical Skin Anesthesia for Subcutaneous Drug Reservoir and Lumbar Punctures in Children Gideon Koren, Daniel S. Halperin, Marinette Wyss and Joseph Kapelushnik	55
5.	Use of EMLA Cream and EMLA Patch in Outpatient Clinics Gideon Koren, Chrisoula Eliopoulos, Shyam Radhakrishnan, Ram Kumar, Paul Hwang and Isabelle Robieux	63
6.	EMLA for Neonatal Circumcision Madlen Gazarian	75
7.	Use of EMLA Cream as a Local Anesthetic for Laceration Repair Michael J. Rieder	89
8.	Effect of Lidocaine-Prilocaine Cream (EMLA) on Injection and Vaccination Pain Anna Taddio and Gideon Koren	101
9.	EMLA Cream for Pain Relief During Arterial Cannulation Laura A. Magee	111
10.	Use of EMLA Cream in Dermatosurgical Interventions of Skin and Genital Mucosa Arnold P. Oranje and Flora B. de Waard-van der Spek	123
11.	Use of EMLA Sterile Cream in the Management of Leg Ulcers Donald Rosenthal	137
12.	Use of EMLA Cream in Hemodialysis Patients Izhar Ul Qamar	145
13.	The Emerging Role of EMLA Cream in Lithotripsy Kathleen Shilalukey	153
14.	Use of EMLA Cream in Otolaryngology Doreen Matsui and Matitiahu Berkovitch	161
15.	The Role of EMLA Cream in Split Skin Harvesting Lennart Ohlsen	169
16.	A Study Investigating the Use of EMLA for Chronic Subcutaneous Drug Administration Matitiahu Berkovitch, Susan Davis Lethbridge, Judy Donsky, Richard Hackman, Graham Sher, Gideon Koren, Nancy Olivieri, Doreen Matsui	187
17.	The Impact of EMLA on the Ethics of Pediatric Research Gideon Koren	193
index		203

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