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Current Studies at Motherisk
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Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
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Pregnancy in Women with Multiple Sclerosis
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Environmental Exposures and Children's Health
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Control of Hypertension in Pregnancy Study
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Trimethoprim-Sulfonamide Combination Therapy
Urinary tract infections in pregnancy
Monica Lee, RPh, Pina Bozzo, Adrienne Einarson, RN and Gideon Koren, MD FRCPCJune 2008
QUESTION
My pregnant patients often present with urinary tract infections. Are the medications commonly used for the management of urinary tract infections safe to use during pregnancy?
ANSWER
Existing data indicate that exposure to penicillins, cephalosporins, fluoroquinolones, nitrofurantoin, or phenazopyridine during pregnancy is not associated with increased risk of fetal malformations. Trimethoprim-sulfamethoxazole should be avoided, if possible, during the first trimester of pregnancy because of the antifolate effect associated with neural tube defects.
QUESTION
Il arrive souvent que mes patientes enceintes présentent une infection des voies urinaires. Les médicaments utilisés couramment pour la prise en charge des infections des voies urinaires sont-ils sans risque durant la grossesse?
RÉPONSE
Les données les plus récentes indiquent que lexposition à la pénicilline, à la céphalosporine, au fluoroquinolone, à la nitrofurantoïne ou à la phénazopyridine durant la grossesse nest pas associée à un risque accru de malformations fœtales. Il faudrait éviter dans la mesure du possible le triméthoprime-sulfaméthoxazole durant le premier trimestre en raison de son effet qui est de contrer lacide folique, associé à des anomalies du tube neural.
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