1-877-439-2744 Motherisk Helpline
1-800-436-8477 Morning Sickness
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416-813-6780 Motherisk Helpline
Pregnancy & Breastfeeding Resources
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Current Studies at Motherisk
The Safety of Diclectin in Breastfeeding
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Alcohol Use during Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) ForumMotherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
Is the drug zofran safe to use in pregnancy for vomiting?
The numerous questions to our NVP Helpline and this NVP Forum about Zofran as a medication for NVP and HG, its frequent reported use (especially in the US), as well as the limited safety information on its use, have prompted Motherisk to conduct a safety study. Pregnant women taking Zofran are invited to call our toll-free Helpline at 1-800-436-8477 to take part in this study.
To date, three case reports have been published, with no adverse effects. One prospective study of 15 women also reported no difference in birth outcome.