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Current Studies at Motherisk
The Safety of Diclectin in Breastfeeding
Neurodevelopment of Children Exposed in-Utero to Chemotherapy for Maternal Breast Cancer (Dr. I Nulman)
Diclegis Surveillance Program Study
Diclectin Surveillance Program Study
Study seeks women between 4 and 12 weeks in their pregnancy with morning sickness (NVP)
Pregnancy in Women with Multiple Sclerosis
Alcohol Use during Pregnancy
Lamisil in Pregnancy
Meridia in Pregnancy
Autoimmune Diseases in Pregnancy Project
The Motherisk Nausea and Vomiting of Pregnancy (NVP) ForumMotherisk receives questions from around the world about morning sickness symptoms, effects, treatments and ways to cope. Those questions and answers are posted here for anyone to read, provided the reader acknowledges and accepts the proviso and disclaimer below.
I have been prescribed DICLECTIN for nausea. I am in my 8th week of my fourth pregnancy and felt that it was difficult to manage three small children and constant nausea. Is there anything i should be worried about ? And can i lessen the dosage according to need?
Diclectin is the approved and safe treatment for NVP in Canada. Diclectin (a Vitamin B6 and doxylamine succinate formulation), has been used for more than 30 years, and has been the subject of 95 studies. Consequently, we can say that the use of this medication will not interfere with a pregnancy, taken at any stage for long or short periods, and will not change or increase the 1% to 3% baseline risk for birth defects that is present in all pregnancies.
Scheduling and dosage are important. Typically the medication works best when taken on a regular basis. Diclectin is delayed (approximately 4 hours after intake) and therefore use when needed is not recommended. Regarding safety, there is no difference whether one, two or four pills are taken daily. There is new evidence that higher doses are also safe. For more information please call our NVP Helpline at 1-800-436-8477